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What side effects may occur?
Less common or rare side effects may include:
- Acne, allergic reaction, altered taste, back pain, blindness, breast development in males, breast pain or enlargement, breathing difficulties, brui
se-like marks on the skin, cataracts, changeable emotions, chest pain, cold, clammy skin, conjunctivitis (pinkeye), coughing, difficulty breathing, difficulty swallowing, double vision, dry eyes, eye
pain, fainting, feeling faint upon arising from a sitting or lying position, feeling of illness, female and male sexual problems, fever, fluid retention, flushing,
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Other medical problems
If Zoloft is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Zoloft with the foll
owing:
- Cimetidine (Tagamet)
- Diazepam (Valium)
- Digitoxin (Crystodigin)
- Flecainide (Tambocor)
- Lithium (Eskalith, Lithobid)
- MAO inhibitor drugs such as the antid
epressants Nardil and Parnate
- Other serotonin-boosting drugs such as Paxil and Prozac
- Other antidepressants such as Elavil and Serzone
- Over-the-counter drugs such as cold remedies
- Propafenone (Rythmol)
- Sumatriptan (Imitrex)
- Tolbutamide (Orinase)
- Warfarin (Coumadin)
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Why is this drug prescribed?
Zoloft can also be used for the type of depression called premenstrual dysphoric disorder (PMDD). This recurring problem is marked by a depressed mood, anxiety or tension, emotional instability, and a
nger or irritability in the two weeks preceding menstruation. Other symptoms may include loss of interest in activities, difficulty concentrating, lack of energy, changes in appetite or sleep patterns
, and feeling out of control.
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How should this medicine be used?
Zoloft is available in capsule and oral concentrate forms. To prepare Zoloft oral concentrate, use the dropper provided. Measure out the amount of concentrate prescribed by your doctor and mix it with
4 ounces of water, ginger ale, lemon/lime soda, lemonade, or orange juice. (Do not mix the concentrate with any other type of beverage.) Drink the mixture immediately; do not prepare it in advance fo
r later use. At times, a slight haze may appear after mixing, but this is normal.
Improvement with Zoloft may not be seen for several days to a few weeks. You should expect to keep taking it
for at least several months.
Zoloft may make your mouth dry. For temporary relief suck a hard candy, chew gum, or melt bits of ice in your mouth.
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Adverse Effects
Autonomic Nervous System Disorders: - Infrequent: Flushing, mydriasis, increased saliva, cold clammy skin. Rare: Pallor.
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Overdose
Establish and maintain an airway, insure adequate oxygenation and ventilation. Activated charcoal, which may be used with sorbitol, may be as or more effective than emesis or lavage, and should be con
sidered in treating overdose.
Cardiac and vital signs monitoring are recommended along with general symptomatic and supportive measures.
There are no specific antidotes for sertral
ine.
Due to the large volume of distribution of sertraline, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit.
In managing overdose,
the possibility of multiple drug involvement must be considered.
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